Hrolfsdottir L , Rytter D , Hammer Bech B , Brink Henriksen T , Danielsen I , Steingrimsdottir L , Olsen SF , Halldorsson TI. - 44611 N - Eur J Clin Nutr 2013 ; in press.
SUBJECT/METHODS:A prospective cohort of 809 Danish pregnant women was recruited in 1988-1989, with offspring follow-up at approximately 20 years of age (n=685). Milk consumption was assessed at gestational week 30 using a food frequency questionnaire. Birth weight and birth length were measured according to standard procedures at delivery and converted to specific z-scores, adjusted for gestational age and gender.
RESULTS:In adjusted models, maternal milk consumption of >/=150 ml/day vs <150 ml/day was associated with 0.32 higher z-scores for birth weight (95% confidence interval (CI) 0.06; 0.58) and 0.34 higher z-scores for birth length (95% CI 0.04; 0.64). At follow up, approximately 20 years later, those offspring whose mothers had consumed >/=150 ml milk/day tended to have 0.19 higher z-scores for height (P=0.16), approximately 8% higher levels of insulin-like growth factor I (P=0.12) and approximately 14% higher insulin levels (P=0.11) compared with offspring whose mothers consumed <150 ml milk/day.
CONCLUSIONS:Our findings add to recent observations that maternal milk consumption may have a growth-promoting effect with respect to weight and length at birth. Furthermore, the results provide some suggestion that this effect may even track into early adult age, although further studies with more statistical power are needed for that purpose.